Pasquale Caponnetto

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1 NCT01387425

Efficacy And Safety Of Smoking Cessation With Varenicline Tartrate In Diabetic Smokers: (DIASMOKE), Caponnetto P., Co-Investigator

This protocol is intended to provide information regarding the efficacy and safety of the nicotine partial agonist varenicline tartrate, at a dose of 1 mg twice daily, for smoking cessation in diabetic subjects who smoke.

 

2. NCT01979796

Antismoking Effects of Electronic Cigarettes in Subjects With Schizophrenia and Their Potential Influence on Cognitive Functioning (SCARIS). Caponnetto P., Principal Investigator

a randomized controlled trial investigating the efficacy and safety of electronic cigarette. The trial will take the form of a prospective 12-month randomized clinical study to evaluate smoking reduction, smoking abstinence and adverse events in schizophrenic smokers not intending to quit. The investigators will also monitor quality of life, neurocognitive functioning and measure participants' perception and satisfaction of the product

 

3. NCT02124187

Smoking Cessation And Reduction in Depression (SCARID). Caponnetto P., Principal Investigator

Evaluate smoking reduction, smoking abstinence and adverse events in depressed smokers not intending to quit.

 

4. NCT01665066

Pharmacokinetic Profile of Toxic Substances and Nicotine in Electronic Cigarettes (KINECIG)California Department of Health Services.  Caponnetto P., Co-Investigator  

The aim of the present study is to compare serum nicotine levels of different e-Cigarette strength with usual cigarettes

 

5. NCT01188239

A Structured Protocol to Evaluate Efficacy and Safety of a Popular Electronic Nicotine Delivery Device (E-Cigarette) Efficacy and Safety of a Popular Electronic Nicotine Delivery Device (E-Cigarette). Caponnetto P., Co-Investigator  

The study's major aim is to investigate the ability of a commercial Electronic Nicotine Delivery Device (E-Cigarette) loaded with low dose nicotine to induce long-term smoking reduction/abstinence in smokers unwilling to quit.

 

6. NCT01194583

Efficacy and Safety of an Electronic Nicotine Delivery Device (E-Cigarette) Without Nicotine Cartridges. Caponnetto P., Co-Investigator  

The study will monitor smoking reduction/abstinence effects, changes in withdrawal symptoms, and adverse events of a currently marketed device in Italy ("Categoria" electronic cigarette - "NO nicotine" cartridges).

 

7. NCT01164072

Efficacy and Safety of an Electronic Nicotine Delivery Device (E-Cigarette). Caponnetto P., Co-Investigator .

The study will monitor smoking reduction/abstinence effects, changes in withdrawal symptoms, and adverse events of a currently marketed device in Italy ("Categoria" electronic cigarette - "ORIGINAL" 7.2 mg nicotine cartridges).

 

8. NCT01195597

Smoking Cessation and Reduction With an Electronic Nicotine Delivery Device (ENDD). Caponnetto P., Co-Investigator .

The study's major aim is to investigate the ability of a commercial Electronic Nicotine Delivery Device (ENDD) to induce long-term smoking reduction/abstinence in smokers unwilling to quit.

 

9. NCT01735487

CogEcig: Cognitive Functioning and Electronic Cigarette. Caponnetto P., Principal-Investigator .

The aim of the present study is to compare cognitive scores (attention, executive function and working memory) of different e-Cigarette strength with usual cigarettes

 

10. NCT02124200

High Cessation Rates in Smokers Using Personal Vaporizers (VAPECIG). Caponnetto P., Co-Investigator .

In this prospective proof-of-concept study we monitored modifications in smoking habits of 50 regular smokers (unwilling to quit) who were asked to switch to a second generation device focusing on smoking reduction and smoking abstinence.

 

 

11. NCT02398487

 

Personal Vaporizer vs Cigalike (VAPECIG 2).Caponnetto P., Co-Investigator .

 

This is a pilot study to compare efficiency and tolerability of a personal vaporizers (PV) new generation electronic cigarette loaded with nicotine e-liquid with cigalike new generation electronic cigarette loaded with nicotine and usual smoking habits, in a group of well characterized regular smokers unwilling to quit.

 

12. Pilot study to assess nicotine/cotinine levels and vaping topography among 24 mg and 0 mg nicotine e-cigarettes and tobacco cigarettes (Pre-Elect). Caponnetto P., Co-Investigator .

 

Assess subjective and physiological effects of nicotine level from use of e-cigarette (24 mg nicotine) compare to conventional cigarette in smokers. Vaping topography was  assessed.

 

 

13. A pilot study to assess subjective and physiological effects of nicotine level from use of e-cigarette compared to conventional cigarette in smokers and dual user: JK study. Caponnetto P., Co-Investigator .

 

Assess subjective and physiological effects of nicotine level from use of e-cigarette (18 mg nicotine) compare to conventional cigarette in smokers and dual user: . Vaping and smokingtopographywasassessed.

 

14. Dipartimento di Psicologia Università di Roma “La Sapienza”, Collaborazione alla costruzione della SAR,  Scala Alessitimica Romana,  (Giannini, Laghi, Baiocco). Caponnetto P., Co-Investigator .

 

Somministrazione questionari, scoring ed analisi dei dati

 

15. Ricerca su "coppia criminale" all'interno del Master di II Livello in Scienze Criminologiche e Penitenziarie, Facoltà di Scienze Politiche Università degli Studi di Catania dal 01-11-2007 al 28-02-2009. Caponnetto P., PI-Investigator .

 

16. Sperimentazione ricerca umanizzazione delle cure codice rosa (codice riservato a vittime di violenza) ASP 3 Catania, UOC Servizio di Psicologia, Pronto Soccorso Ospedale Acireale (Catania) dal 01-07-2016 a oggi. Caponnetto P., Co-Investigator .

 

17. The Perceived Influence of Sensory Sensations and Cues on Tobacco Cessation Outcomes Among E-Cigarette Users. (Sensorial).Caponnetto P., Principal-Investigator , Italian Site.

 

1) Examine the perceived experiences of sensory sensations and cues among e-cigarette users 2) Assess e-cigarette users’ perceptions of the influences of these experiences on tobacco smoking cessation outcomes compared with previously used US FDA approved cessation medications.

 

18. NCT03075202

 

Role of an E-cigarette on Smoking Displacement in Smokers With Schizophrenia, collaboration with City University of New York and Weill Cornell University New York:Caponnetto P., Principal-Investigator , Italian Site.The primary endpoint of this study is the proportion of study participants with a self-reported complete displacement from tobacco cigarette smoking - not even a puff in between study visits, along with confirmatory eCO values ≤10 ppm at each study visit