Davide Barbagallo

Associate Professor of Cellular and Experimental Biology [BIOS-10/A]
Membership Section: Biology and Genetics

Keywords

Regulation of gene expression; microrna; circular RNA; ceRNA

Dr Davide Barbagallo (DB), married, three children, held a PhD in Biology, human genetics and bioinformatics in 2009 (supervisor: Prof. Michele Purrello), both from the University of Catania, Italy. From 2009 to 2019 DB carried on his research activity as PostDoc at University fo Catania, under the supervision of Prof. Michele Purrello. and Prof. Cinzia Di Pietro. In 2017 DB held specialization in medical genetics at University of Messina by discussing a thesis on the involvement of circular RNAs (circRNAs) in the pathogenesis of glioblastoma multiforme (GBM). His early studies were focused on the involvement of a set of transcripts belonging to the apoptotic machinery and to the class of microRNAs (miRNAs) in the etiology of diabetes mellitus. Since 2016, his scientific interests shifted towards the study of brain cancer, focusing on the involvement of miRNAs and circRNAs in its pathogenesis. DB collaborated to research activities on the involvement of non-coding RNAs in the field of human infertility and cancer. In 2017, thanks to the win of a travel grant sponsored by Umberto Veronesi Foundation, DB moved to Aarhus University (Denmark) where he learnt the main techniques to study the function of circRNAs and applied this knowledge to the study of functional involvement of circSMARCA5 in the pathogenesis of GBM, under the guidance of Dr. Thomas Hansen. DB has authored or co-authored more than 40 peer-reviewed scientific publications on impacted international journals, up today. Since 2020 DB is Assistant Professor of Applied Biology (SSD BIO/13) at University of Catania. Since 2023 DB is Associate Professor of Applied Biology (SSD BIO/13) at University of Catania.

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VIEW THE COURSES FROM THE A.Y. 2022/2023 TO THE PRESENT

Academic Year 2021/2022


Academic Year 2020/2021


Academic Year 2019/2020


Academic Year 2018/2019


Academic Year 2017/2018


Academic Year 2016/2017


Academic Year 2015/2016

The research activity of Dr. Davide Barbagallo is focused on:

1) the mechanism of regulation of gene expression mediated by "non-coding" RNAs (ncRNAs), in particular microRNAs and circular RNA (circRNA).

2) the identification of biomarkers, within the aforementioned classes of ncRNAs, both in tissue biopsies and in liquid biopsies

The experimental model of major interest is glioblastoma multiforme but of course the experimental approach used allow investigations to be extended to other models, beyond cancer